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When to measure Thyroxine level after taking drug
I have a approximately 10 year old male cocker spaniel who is taking
Thyroxine for a thyroid problem. The vet said he would measure the thyroxine level 3 hours after the drug was taken. Is this the correct time to do this? I have read on various internet resources that it should be 4-6 hours. The drug has been measured several times. The results a Canine total thyroxine(t4) 9.99 nmol/litre 14.4 nmol/litre 24.1 nmol/litre. What is the normal range for this? |
#2
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When to measure Thyroxine level after taking drug
"Polly Filler" wrote in message
... I have a approximately 10 year old male cocker spaniel who is taking Thyroxine for a thyroid problem. The vet said he would measure the thyroxine level 3 hours after the drug was taken. Is this the correct time to do this? I have read on various internet resources that it should be 4-6 hours. Protocols may be different with different labs. If they always measure 3 hours post pill then I'd imagine the results they expect (and reference ranges) are going to be based on 3 hours post pill. Anyone out there know the kinetics of thyroxine in a dog? (absorption rate and half life specifically). These two numbers will tell you how sensitive the timing of the test is. I've googled around a bit, but I'm finding conflicting results. Dale |
#3
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When to measure Thyroxine level after taking drug
Dale Atkin wrote:
"Polly Filler" wrote in message ... I have a approximately 10 year old male cocker spaniel who is taking Thyroxine for a thyroid problem. The vet said he would measure the thyroxine level 3 hours after the drug was taken. Is this the correct time to do this? I have read on various internet resources that it should be 4-6 hours. Protocols may be different with different labs. If they always measure 3 hours post pill then I'd imagine the results they expect (and reference ranges) are going to be based on 3 hours post pill. Anyone out there know the kinetics of thyroxine in a dog? (absorption rate and half life specifically). These two numbers will tell you how sensitive the timing of the test is. I've googled around a bit, but I'm finding conflicting results. Dale Thank you for that. (I'm thanking you on behalf of my father, who posted the original request). My father was under the impression the vet attempts to measure the peak value. From what I can gather the half-life is about 7 hours, but I've no idea how rapidly it is absorbed once taken. |
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